This website is intended for US residents.

Hero image Hero image

Resources

Actor portrayal

Support at your fingertips

Find helpful resources about managing hereditary angioedema and starting EKTERLY.

  • EKTERLY® (sebetralstat) patient brochure
    EKTERLY Patient Brochure

    Discover more about EKTERLY, including how to take it, study results, safety information, and how to get support during your treatment journey.

    DOWNLOAD

    EN

    EMAIL

    EN
  • Doctor discussion guide for EKTERLY® (sebetralstat)
    Doctor Discussion Guide

    Get the conversation started about EKTERLY with your doctor.

    DOWNLOAD

    EN

    EMAIL

    EN
  • KalVista Cares™ Brochure
    KalVista Cares Overview

    Learn more about KalVista Cares and how we can provide you the support you need to stay on track.

    DOWNLOAD

    EN

    EMAIL

    EN

Here are some committed organizations that can offer more information about HAE.

US Hereditary Angioedema Association logo
Hereditary Angioedema Association

The US Hereditary Angioedema Association (HAEA) is a 501(c)(3) nonprofit advocacy and research organization serving people living with the rare genetic condition HAE and their families.

Go
National Organization for Rare Diseases logo
National Organization for Rare Disorders

The National Organization for Rare Disorders (NORD) is a 501(c)(3) nonprofit dedicated to supporting individuals with rare diseases through advocacy, research, and patient assistance programs. It connects patients, caregivers, and researchers to advance treatment access and policy improvements.

Go
prev
next

Questions about EKTERLY?

Get answers to the most frequently asked questions about EKTERLY.

About EKTERLY
  • What is on-demand treatment
    for HAE?

    Icon image

    On-demand treatment (also known as rescue or acute treatment) is used to treat HAE
    attacks as they occur and can help reduce the severity and duration of HAE attacks.

    Learn about managing HAE attacks.
  • How does EKTERLY work?

    Icon image

    EKTERLY works by blocking plasma kallikrein, which is a protein that plays a key role in swelling
    in hereditary angioedema (HAE) attacks.

    Learn about the science behind EKTERLY.
Taking EKTERLY
  • Can I take more than 1 dose of
    EKTERLY?

    Icon image

    Yes. One dose of EKTERLY is 2 pills
    (600 mg). You can take more than 2 pills of EKTERLY if your symptoms have not resolved. Make sure to take EKTERLY exactly as your doctor prescribes. Do not take more than 4 EKTERLY pills within 24 hours.

    Learn more about taking EKTERLY.
  • Where should I store EKTERLY?

    Icon image

    Store EKTERLY in the package that it comes in so you can have it ready whenever you need
    it. Make sure to keep EKTERLY at room temperature, between 68°F to 77°F (20°C to 25°C),
    and out of reach from children.

  • Are there any side effects that
    I should expect?

    Icon image

    The safety of EKTERLY was similar to placebo. The most commonly reported side effect in clinical trials was headache. No serious side effects were reported.

    Learn about the safety of EKTERLY.
  • What is EKTERLY made of?

    Icon image

    EKTERLY is soy and gluten free and contains no more than 0.05 mg of free sodium per pill
    (0.01%).

Patient Support Program
  • How can I learn about patient support for people taking EKTERLY?

    Icon image

    Check out our FAQs on the Patient Support Program page or call us at 1-844-432-3322.
    Our team is available Monday-Friday between 8:30 am-8 pm ET.

Send this resource straight to your inbox!

All fields required.

Enter your first name.

Enter your last name.

Enter a valid email address.

By registering, you confirm you are a US resident and agree to receive educational information, materials, updates, and other content from KalVista Pharmaceuticals, Inc. For more information regarding our collection and use of personal information, see our Privacy Policy.

Please verify that you are human.

Image
Right arrow

INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS EKTERLY® (sebetralstat)?

EKTERLY is a prescription medicine used to treat sudden (acute) attacks of hereditary angioedema (HAE) in adults and children aged 12 years of age and older. It is not known if EKTERLY is safe and effective in children under 12 years of age.

IMPORTANT SAFETY INFORMATION

Before taking EKTERLY, tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or planning to become pregnant. It is not known if EKTERLY can harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if EKTERLY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking EKTERLY.
  • Have liver problems.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking EKTERLY with certain other medicines can cause side effects or affect how well EKTERLY or the other medicines work. Especially tell your healthcare provider if you take any of the following, as their use with EKTERLY is not recommended: itraconazole, phenytoin, efavirenz.

Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.

What are the possible side effects of EKTERLY?

The most common side effects of EKTERLY include headache. For more information, ask your healthcare provider or pharmacist. Talk to your doctor for medical advice about side effects.

You are encouraged to report side effects related to KalVista products by calling 1-855-258-4782. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for full Prescribing Information, including Patient Information.