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Managing HAE Attacks
HAE can be managed with
2 types of treatment
Even if you’re on preventative therapy, you should always have an on-demand hereditary angioedema (HAE) treatment (also known as rescue or acute therapy) on you so you can respond to attacks if and when they happen. If you aren’t currently prescribed an on-demand treatment, talk to your doctor about your options.
-
Preventative treatment
Preventative treatment is taken regularly
with the goal of reducing the number and
severity of HAE attacks. -
On-demand treatment
On-demand treatment is used to treat HAE
attacks as they occur and can help reduce
their length and severity.
Preventative therapies alone do not eliminate the burden of HAE attacks
Attacks cause significant disruptions to the lives of people with HAE, requiring them to modify their lifestyles and daily routines.
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In a 2021 analysis,
over a 12-month span,
90% of people
on preventative treatment reported
still experiencing attacks.*
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12 doses per year
On average per year, people on
preventative treatment requested12 doses of on-demand treatment
to treat potential attacks.†
Delays and lack of treatment of HAE attacks seen with previous on-demand therapies
Prior to the approval of oral on-demand therapy, people often delayed treatment or didn’t treat
attacks at all.
-
In a 2023 survey, patients waited
3.8 hours
on average to treat after the first
sign of an attack.‡
-
In a 2022 survey,
57%
of patients didn't treat
all their attacks.§
In a 2022 survey, up to
83%
of people with HAE were anxious when anticipating the use of on-demand injections or infusions.§
*Data were derived from a US-based, retrospective, real-world survey using the Adelphi HAE Disease Specific Program database (July-November 2021).
†±19.7 doses of on-demand treatment. Data were derived from a retrospective, real-world study of 328 patients taking long-term prophylaxis using the IQVIA PharMetrics® Plus database (January 2016-September 2023).
‡Results from a 2023 HAE Association survey of 94 people taking either on-demand treatment or both on-demand and preventative treatment.
§Results from a 2022 HAE Association survey of 107 people taking either on-demand treatment or both on-demand and preventative treatment.
On-demand treatments can
halt attack progression,
but
it takes time for your body
to clear the swelling. Treating
as early
as
possible may lead to less severe attacks and a
faster recovery.
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