This website is intended for US residents.

background background

Taking
EKTERLY

Actor portrayal

Taking EKTERLY is quick and convenient

Take one dose (2 pills) at a time. You may take a second dose after 3 hours, with no more than 4 pills
in 24 hours.

  • EKTERLY® (sebetralstat) doesn't need to be refrigerated or prepared

    No preparation, setup,
    or refrigeration required

  • EKTERLY® (sebetralstat) can be taken with or without food

    Can be taken with or
    without food

  • EKTERLY® (sebetralstat) is film-coated for easy swallowing

    Film-coated pills for
    easy swallowing

Each box of EKTERLY contains 4 pills.

EKTERLY is free of gluten and soy.

How quickly do you take your on-demand treatment after you recognize HAE attack symptoms?

move icon

Move the slider to select your answer.

ASAP

30 minutes

2 hours

4+ hours

3.8 hours

was the average time people with
HAE waited to treat an attack*

*Results from a 2023 HAE Association survey of 94 people taking either on-demand treatment or both on-demand and preventative treatment.

Don’t wait to treat your HAE attack

People took EKTERLY for hereditary angioedema (HAE) attacks in a median time of:

  • 41 minutes

    after attack onset in
    the clinical trial

  • 10 minutes

    after attack onset in
    an
    ongoing extension study

  • Digestive system

    ABDOMINAL ATTACKS can trigger vomiting and diarrhea, but EKTERLY is designed to be quickly absorbed higher up in your digestive system than where these attacks typically occur.

    Learn more about how EKTERLY works.

  • Digestive system

    There have been no reports of difficulty swallowing EKTERLY during LARYNGEAL ATTACKS.

EKTERLY® (sebetralstat) doctor discussion guide

Talk to your doctor about starting EKTERLY today.

Get the discussion guide

INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS EKTERLY® (sebetralstat)?

EKTERLY is a prescription medicine used to treat sudden (acute) attacks of hereditary angioedema (HAE) in adults and children aged 12 years of age and older. It is not known if EKTERLY is safe and effective in children under 12 years of age.

IMPORTANT SAFETY INFORMATION

Before taking EKTERLY, tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or planning to become pregnant. It is not known if EKTERLY can harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if EKTERLY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking EKTERLY.
  • Have liver problems.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking EKTERLY with certain other medicines can cause side effects or affect how well EKTERLY or the other medicines work. Especially tell your healthcare provider if you take any of the following, as their use with EKTERLY is not recommended: itraconazole, phenytoin, efavirenz.

Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.

What are the possible side effects of EKTERLY?

The most common side effects of EKTERLY include headache. For more information, ask your healthcare provider or pharmacist. Talk to your doctor for medical advice about side effects.

You are encouraged to report side effects related to KalVista products by calling 1-855-258-4782. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for full Prescribing Information, including Patient Information.